White matter abnormalities and cognitive function in euthymic patients with bipolar disorder and major depressive disorder.

Yoshikazu MasudaGo OkadaMasahiro TakamuraChiyo ShibasakiAtsuo YoshinoSatoshi YokoyamaNaho IchikawaShiho OkuhataTetsuo KobayashiShigeto YamawakiYasumasa Okamoto

Published in: Brain and behavior (2020)

The significant reduction of white matter integrity in the corpus callosum in BD, compared to MDD, was associated with an impairment of sustained attention. This result promotes the understanding of the significance of white matter integrity in mood disorders.

Keyphrases

bipolar disorder
white matter
major depressive disorder
multiple sclerosis
working memory
depressive symptoms
sleep quality