The cholesterol esterification inhibitor avasimibe suppresses tumour proliferation and metastasis via the E2F-1 signalling pathway in prostate cancer.
Kangping XiongGang WangTianchen PengFenfang ZhouSiming ChenWei LiuLingao JuYu XiaoKaiyu QianXing-Huan WangPublished in: Cancer cell international (2021)
Our results suggest that avasimibe can suppress tumour proliferation and metastasis via the E2F-1 signalling pathway. These findings demonstrate the potential of avasimibe as a new effective drug for PCa treatment.