The cholesterol esterification inhibitor avasimibe suppresses tumour proliferation and metastasis via the E2F-1 signalling pathway in prostate cancer.

Kangping XiongGang WangTianchen PengFenfang ZhouSiming ChenWei LiuLingao JuYu XiaoKaiyu QianXing-Huan Wang

Published in: Cancer cell international (2021)

Our results suggest that avasimibe can suppress tumour proliferation and metastasis via the E2F-1 signalling pathway. These findings demonstrate the potential of avasimibe as a new effective drug for PCa treatment.

Keyphrases

prostate cancer
signaling pathway

emergency department
low density lipoprotein

combination therapy
climate change

replacement therapy
electronic health record