Differential Activation of Unconventional T Cells, Including iNKT Cells, in Alcohol-Related Liver Disease.

Idania MarreroIgor MaricicTimothy R MorganAndrew A StolzBernd SchnablZhang-Xu LiuHidekazu TsukamotoVipin Kumar

Published in: Alcoholism, clinical and experimental research (2020)

We found that the 3 unconventional T cells are activated in ALD patients showing interesting differences in their frequency and cytokine production profile between SAH and ChA patients. In the iG murine model of chronic ASH, iNKT cells are also activated secreting proinflammatory cytokines suggesting their involvement in liver disease.

Keyphrases

end stage renal disease
induced apoptosis
ejection fraction
newly diagnosed
peritoneal dialysis
endoplasmic reticulum stress
drug induced