In vivo protein expression changes in mouse livers treated with dialyzed coffee extract as determined by IP-HPLC.
Cheol Soo YoonMin Keun KimYeon Sook KimSuk Keun LeePublished in: Maxillofacial plastic and reconstructive surgery (2018)
These observations suggested that DCE-2.5 and DCE-5 were safer and more beneficial to murine hepatocytes than DCE-10. It was also found that murine hepatocytes treated with DCE showed mild p53-mediated apoptosis, followed by cellular proliferation and growth devoid of fibrosis signaling (as determined by IP-HPLC), and subsequently progressed to rapid cellular regeneration and wound healing in the absence of any inflammatory reaction based on histologic observations.
Keyphrases
- contrast enhanced
- ms ms
- wound healing
- simultaneous determination
- oxidative stress
- stem cells
- high performance liquid chromatography
- liver injury
- mass spectrometry
- solid phase extraction
- magnetic resonance imaging
- tandem mass spectrometry
- magnetic resonance
- computed tomography
- drug induced
- anti inflammatory
- high resolution