(Radio)fluoroclick Reaction Enabled by a Hydrogen-Bonding Cluster.

Xiaojun ZengJunling LiChin K NgGerald B HammondBo Xu

Published in: Angewandte Chemie (International ed. in English) (2018)

We have developed a widely applicable nucleophilic (radio)fluoroclick reaction of ynamides with readily available and easy-to-handle KF(18 F). The reactions exhibited high functional-group tolerance and needed only an ambient atmosphere. This 18 F addition to C-C unsaturated bonds proceeded with extraordinarily high radiochemical yields.

Keyphrases

air pollution
particulate matter