Extensive frontal focused ultrasound mediated blood-brain barrier opening for the treatment of Alzheimer's disease: a proof-of-concept study.

So Hee ParkKyoungwon BaikSeun JeonWon Seok ChangByoung Seok YeJin Woo Chang

Published in: Translational neurodegeneration (2021)

The repeated and extensive BBB opening in the frontal lobe is safe and feasible for patients with AD. In addition, the BBB opening is potentially beneficial for amyloid removal in AD patients.

Keyphrases

blood brain barrier
end stage renal disease
cerebral ischemia
newly diagnosed
ejection fraction
chronic kidney disease
functional connectivity
peritoneal dialysis
cognitive decline
brain injury
mild cognitive impairment
smoking cessation
replacement therapy