Evaluation of pretreatment ADC values as predictors of treatment response to neoadjuvant chemotherapy in patients with breast cancer - a multicenter study.
Alexey SurovMaciej PechHans-Jonas MeyerAlmir G V BitencourtHiroshi FujimotoGabrielle C BaxterGorane SantamaríaFiona J GilbertAndreas WienkePublished in: Cancer imaging : the official publication of the International Cancer Imaging Society (2022)
The pretreatment ADC-value is associated with pathological complete response after NAC in breast cancer patients. This could aid in clinical routine to reduce treatment toxicity for patients, who would not benefit from NAC. However, this must be tested in further studies, as the overlap of the ADC values in both groups is too high for clinical prediction.