Percutaneous left atrial appendage occlusion and risk of stroke, hospitalized bleeding and death in Medicare beneficiaries.
Wendy WangLin Yee ChenRob F WalkerAlvaro AlonsoFaye L NorbyKamakshi LakshminarayanPamela L LutseyPublished in: Pharmacoepidemiology and drug safety (2024)
In this analysis of real-world AF patients, percutaneous LAAO versus OAC use was associated with similar risk of death, nonsignificantly elevated risk of stroke, and an elevated risk of bleeding in the post-procedural period. Overall, these results support results of randomized trials that percutaneous LAAO may be an alternative to OAC use for patients with contraindications.