Drug-induced interstitial lung disease caused by olaparib: three case reports and review of the Japanese Adverse Drug Event Report database and literature.
Hiroshi IshimotoNoriho SakamotoTakashi KidoMutsumi OzasaShin TsutsuiMayako MoriDaichi SetoguchiShinnosuke TakemotoYasushi ObaseYuji IshimatsuChiharu TomonagaKanako MatsumotoSachiko MorisakiKiyonori MiuraHiroshi MukaePublished in: BMC pulmonary medicine (2023)
DIILD caused by olaparib in Japan, including the present three cases, commonly presents with GGO, similar to hypersensitivity pneumonitis on chest CT. The prognosis for the majority of patients is favorable; however, there have been instances of severe cases. Early recognition of drug-induced lung injury and further accumulation of cases is important.
Keyphrases
- drug induced
- adverse drug
- liver injury
- interstitial lung disease
- systemic sclerosis
- end stage renal disease
- chronic kidney disease
- systematic review
- ejection fraction
- rheumatoid arthritis
- idiopathic pulmonary fibrosis
- peritoneal dialysis
- computed tomography
- emergency department
- prognostic factors
- early onset
- magnetic resonance
- positron emission tomography
- contrast enhanced
- patient reported