Plasma proteomic signature of the risk of developing mobility disability: A 9-year follow-up.

Yusuke OsawaRichard D SembaGiovanna FantoniJulián CandiaAngélique BiancottoToshiko TanakaStefania BandinelliLuigi Ferrucci

Published in: Aging cell (2020)

CTSS, GDF15, and THBS2 are novel blood biomarkers associated with new mobility disability in community-dwelling individuals. Overall, our analysis suggests that cellular senescence and inflammation should be targeted for prevention of mobility disability.

Keyphrases

community dwelling
multiple sclerosis
oxidative stress
dna damage
endothelial cells
stress induced
label free
data analysis