Childhood Adversities and Physical and Mental Health Outcomes in Adults Living with HIV: Findings from the Ontario HIV Treatment Network Cohort Study.
Tsegaye BekeleEvan J CollinsRobert G MaunderSandra GardnerSergio RuedaJason GlobermanThao Lan LeJon HunterAnita BenoitSean B RourkeThe Ohtn Cohort Study TeamPublished in: AIDS research and treatment (2018)
We sought to estimate the prevalence of childhood adversity and examine its relationship with health outcomes among people living with HIV. Study participants included 1409 adults living with HIV and receiving care in Toronto, Canada. Data on childhood adversity, health behaviors, HIV outcome measures, depression, and health-related quality of life (HRQOL) were collected through face-to-face interviews and medical records. Statistical analyses included multivariable linear and logistic regression modeling. The prevalence of any childhood adversity was 71% (individual types ranged from 11% to 44%) and higher prevalence was associated with younger age, Indigenous or African/Caribbean/Black ethnicity, lower socioeconomic status, and higher rates of cigarette smoking and nonmedicinal drug use. Greater number of childhood adversities was associated with greater odds of depression and decreasing mental HRQOL. HIV care providers need to screen for childhood adversities and address childhood trauma within the context of HIV care.
Keyphrases
- early life
- healthcare
- mental health
- childhood cancer
- public health
- antiretroviral therapy
- risk factors
- hiv infected
- human immunodeficiency virus
- hiv positive
- depressive symptoms
- hepatitis c virus
- hiv testing
- high throughput
- machine learning
- electronic health record
- men who have sex with men
- risk assessment
- young adults
- south africa
- climate change
- chronic pain
- smoking cessation
- data analysis
- trauma patients