Macrophage and CD8 T cell discordance are associated with acute lung allograft dysfunction progression.

Daniel R CalabreseChristina A EkstrandShivaram YellamilliJonathan P SingerSteven R HaysLorriana E LeardRupal J ShahAida VenadoNicholas A KolaitisAlyssa PerezAlexis CombesJohn R Greenland

Published in: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation (2024)

BAL anti-inflammatory macrophages may protect against CLAD by suppressing CD8 T cells. These populations merit functional and longitudinal assessment in additional cohorts.

Keyphrases

anti inflammatory
liver failure
respiratory failure
adipose tissue
oxidative stress
drug induced
aortic dissection
kidney transplantation