A Comparative Study on the Effect of Exosomes Secreted by Mesenchymal Stem Cells Derived from Adipose and Bone Marrow Tissues in the Treatment of Osteoarthritis-Induced Mouse Model.

Hoda Fazaeli Naser Kalhor Leila Naserpour Faezeh Davoodi Asl Mohsen Sheykhhasan Seyed Kamal Eshagh Hosseini Mohammad Rabiei Azar Sheikholeslami

Published in: BioMed research international (2021)

BM-MSCs secreted exosomes in comparison with AD-MSCs could be considered as a better therapeutic option to improve osteoarthritis and exhibit potential as a disease-modifying osteoarthritis cell-free product.

Keyphrases

mesenchymal stem cells
bone marrow
cell free
umbilical cord
rheumatoid arthritis
mouse model
knee osteoarthritis
cell therapy
gene expression
adipose tissue
high glucose
stem cells
diabetic rats
drug induced
risk assessment
endothelial cells
human health
replacement therapy