Blockade of the pentraxin 3/CD44 interaction attenuates lung injury-induced fibrosis.

Jhih-Ying ChiYu-Wei HsiaoHsin-Yin LiangTang-Hsiu HuangFeng-Wei ChenChen-Yang ChenChiung-Yuan KoChao-Chun ChengJu-Ming Wang

Published in: Clinical and translational medicine (2022)

The present study reveals new insights into the involvement of the PTX3/CD44 axis in fibrosis and suggests PTX3 as a promising therapeutic target in fILD patients.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
prognostic factors
high glucose
oxidative stress
nk cells
liver fibrosis
drug induced