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Lymphatic-to-blood vessel transition in adult microvascular networks: A discovery made possible by a top-down approach to biomimetic model development.

Mohammad S AzimiJessica M MotherwellNicholas A HodgesGarret R RittenhouseDima MajbourStacey L PorvasnikChristine E SchmidtWalter Lee Murfee
Published in: Microcirculation (New York, N.Y. : 1994) (2019)
Our results reveal the ability for lymphatic vessels to transition into blood vessels in adult microvascular networks and discover a new paradigm for investigating lymphatic/blood endothelial cell dynamics during microvascular remodeling.
Keyphrases
  • lymph node
  • endothelial cells
  • small molecule
  • genome wide
  • high throughput
  • dna methylation
  • childhood cancer
  • network analysis