A multicenter retrospective study of heterogeneous tissue aggregates obstructing ventricular catheters explanted from patients with hydrocephalus.

Prashant HariharanJeffrey SondheimerAlexandra PetrojJacob GluskiAndrew JeaWilliam E WhiteheadSandeep SoodSteven D HamBrandon G RocqueNeena I MarupudiJames P McAllisterDavid LimbrickMarc R Del BigioCarolyn A Harris

Published in: Fluids and barriers of the CNS (2021)

Our data show that age of the first surgery and length of time a VC is implanted are factors that influence the degree of VC obstruction. The tissue aggregates obstructing VCs are composed predominantly of astrocytes and macrophages; microglia have a relatively small presence.

Keyphrases

minimally invasive
heart failure
left ventricular
electronic health record
inflammatory response
coronary artery bypass
big data
cerebrospinal fluid
clinical trial
machine learning
coronary artery disease
spinal cord injury
neuropathic pain
data analysis
atrial fibrillation
catheter ablation