Integrating circulating T follicular memory cells and autoantibody repertoires for characterization of autoimmune disorders.

Emily M HarrisSarah ChamseddineAnne ChuLeetah SenkpeilMatthew NikiciukAmer Al-MusaBrian WoodsElif OzdoganSarife SakerDavid P Hoytema van KonijnenburgChristina S K YeeRyan NelsonPui LeeOlha HalyabarRebecca C HaleMegan Day-LewisLauren A HendersonAlan A NguyenMegan ElkinsToshiro K OhsumiMaria Gutierrez-ArcelusJanique M PeyperCraig D PlattRachael F GraceBrenna LaBereJanet Chou

Published in: medRxiv : the preprint server for health sciences (2024)

cTfm subsets as well as total burden of autoantibodies. Our findings suggest that these approaches are particularly relevant to patients with rare autoimmune disorders for whom target antigens and prognosis are often unknown.

Keyphrases

induced apoptosis
multiple sclerosis
cell cycle arrest
systemic lupus erythematosus
drug induced
dendritic cells
endoplasmic reticulum stress
peripheral blood
signaling pathway
cell death