The Influence of Gestational Diabetes Mellitus upon the Selected Parameters of the Maternal and Fetal System of Insulin-Like Growth Factors (IGF-1, IGF-2, IGFBP1-3)-A Review and a Clinical Study.

Published in: Journal of clinical medicine (2020)

Gestational diabetes mellitus does not significantly affect the concentrations of IGF-1, -2, IGFBP-3 in the peripheral blood and umbilical cord blood, but has the greatest influence on maternal and fetal IGFBP-2 concentrations. A positive correlation between the concentration of IGF-1 in umbilical cord blood and the length of a newborn suggests an influence of IGF-1 on the process of fetal development.

Keyphrases

umbilical cord
mesenchymal stem cells
pi k akt
binding protein
growth hormone
pregnancy outcomes
peripheral blood
pregnant women
type diabetes
birth weight
signaling pathway
clinical trial
metabolic syndrome
weight gain
gestational age