Platelet-rich fibrin/aspirin complex promotes alveolar bone regeneration in periodontal defect in rats.
J DuS MeiL GuoY SuH WangY LiuZ ZhaoS WangYi LiuPublished in: Journal of periodontal research (2017)
Aspirin/salicylic acid could be sustained-released from PRF/aspirin complex, which could inhibit inflammation and improve the function of mesenchymal cells. The data might provide a new safe and easy clinical therapeutic strategy to promote periodontal bone reparation.
Keyphrases
- bone regeneration
- low dose
- cardiovascular events
- antiplatelet therapy
- induced apoptosis
- oxidative stress
- anti inflammatory drugs
- bone marrow
- cell cycle arrest
- stem cells
- cardiovascular disease
- bone mineral density
- acute coronary syndrome
- coronary artery disease
- electronic health record
- endoplasmic reticulum stress
- type diabetes
- signaling pathway
- soft tissue
- postmenopausal women
- body composition
- atrial fibrillation
- pi k akt