Combined Focused Next-Generation Sequencing Assays to Guide Precision Oncology in Solid Tumors: A Retrospective Analysis from an Institutional Molecular Tumor Board.
Thomas S TarawnehFiona R RodepeterJulia Teply-SzymanskiPetra RossVera KochClemens ThölkenJonas A SchäferNiklas GremkeHildegard I D MackJudith GoldJorge Riera-KnorrenschildChristian WilhelmAnja RinkeMartin MiddekeAndreas KlemmerMarcel RomeyAkira HattesohlMoritz JesinghausChristian GörgJens FigielHo-Ryun ChungThomas WündischAndreas NeubauerCarsten DenkertElisabeth K M MackPublished in: Cancers (2022)
The combined focused sequencing assays detected targetable alterations in the majority of patients. Patient benefits appeared to lie in the same range as with large-scale sequencing approaches.