The (non-)sense of detecting anti-cardiolipin and anti-β2glycoprotein I IgM antibodies in the antiphospholipid syndrome.
Walid ChayouaHilde KelchtermansJean-Christophe GrisGary W MooreJacek MusiałDenis WahlPhilip G de GrootBas de LaatKatrien M J DevreesePublished in: Journal of thrombosis and haemostasis : JTH (2019)
Our data support testing for aCL and aβ2GPI IgM in women suspected of obstetric APS. However, no added value was found for testing IgM in patients suspected of thrombotic APS. Still, IgM aPL might be useful as a second-line test to improve thrombotic risk stratification.