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HER2 intratumoral heterogeneity is independently associated with incomplete response to anti-HER2 neoadjuvant chemotherapy in HER2-positive breast carcinoma.

Yanjun HouHiroaki NittaLai WeiPeter M BanksBryce PortierAnil V ParwaniZaibo Li
Published in: Breast cancer research and treatment (2017)
HER2 ITH analyses conducted with GPA method revealed that HER2 ITH is an independent factor predicting incomplete response to anti-HER2 neoadjuvant chemotherapy.
Keyphrases
  • neoadjuvant chemotherapy
  • locally advanced
  • lymph node
  • sentinel lymph node
  • single cell
  • rectal cancer
  • radiation therapy