Our study suggested a potential causal effect of damaged kidney function on kidney cancer. EGFRcrea and UACR might be causally associated with kidney cancer, especially when patients were comorbid with obesity or diabetes. We called for larger sample-size studies to further unravel the underlying causal relationship and the exact mechanism.
Keyphrases
- papillary thyroid
- squamous cell
- type diabetes
- end stage renal disease
- metabolic syndrome
- cardiovascular disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- squamous cell carcinoma
- weight loss
- lymph node metastasis
- adipose tissue
- physical activity
- prognostic factors
- climate change
- glycemic control
- high fat diet induced