Impact of Biotin Supplementation on Human Chorionic Gonadotropin Immunoassays Utilizing Biotin-Streptavidin Binding Methods in Urine.

Jenna M GoodrumVinod S NairChad MooreAndre K CrouchDaniel EichnerGeoffrey D Miller

Published in: Clinical chemistry (2023)

Biotin supplementation can severely suppress urinary hCG values in assays utilizing biotin-streptavidin binding methods and therefore these types of assays are not recommended for use in urine samples containing high levels of biotin. Clinicaltrials.gov Registration Number: NCT05450900.

Keyphrases

endothelial cells
high throughput
dna binding
transcription factor
induced pluripotent stem cells