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Inflammatory myofibroblastic tumour of the larynx: report of a case.

Andrea ColizzaPiero Giuseppe MelianteSamantha DonsanteMara RiminucciAntonio GrecoMarco De VincentiisAlessandro Corsi
Published in: Ear, nose, & throat journal (2022)
Only 0.3-1% of laryngeal cancer are non-squamous cell neoplasms. Of these, a rare entity is inflammatory myofibroblastic tumour (IMT), in which anaplastic lymphoma kinase-1 (ALK-1) is frequently expressed. Just 50 cases of IMT have been reported. Therefore, many otolaryngologists may be unfamiliar with this type of tumour and be prone to its over- or undertreatment.We report a case of ALK-1-negative IMT treated with transoral endoscopic excision and disease-free 6 months after surgery.
Keyphrases
  • squamous cell
  • oxidative stress
  • advanced non small cell lung cancer
  • papillary thyroid
  • diffuse large b cell lymphoma
  • protein kinase
  • epidermal growth factor receptor
  • lymph node metastasis