Clinical benefit of eculizumab in patients with no transfusion history in the International Paroxysmal Nocturnal Haemoglobinuria Registry.

Antonio M AlmeidaCamille BedrosianAlexander ColePetra MuusHubert SchrezenmeierJeffrey SzerWendell F Rosse

Published in: Internal medicine journal (2018)

Significant LDH reduction and clinically meaningful improvement in fatigue were observed in patients with PNH and HDA treated with eculizumab versus untreated patients, irrespective of transfusion history.

Keyphrases

end stage renal disease
newly diagnosed
cardiac surgery
ejection fraction
chronic kidney disease
blood pressure
atrial fibrillation
obstructive sleep apnea
prognostic factors
peritoneal dialysis
sickle cell disease
sleep apnea
depressive symptoms