Outcomes Related to New Persistent Opioid Use after Surgery or Trauma: A population-based Cohort Study.
Jiayi GongPeter JonesKebede BeyeneChris FramptonAmy Hai Yan ChanPublished in: Annals of surgery (2024)
Among opioid-naive patients who received opioids after surgery or trauma, POU was associated with worse outcomes, including increased mortality. Further investigation is warranted to understand the reasons for continued opioid use beyond 90 days and mechanisms associated with harm.