Phytochemicals inhibit migration of triple negative breast cancer cells by targeting kinase signaling.

Pradip Shahi ThakuriMegha GuptaSunil SinghRamila JoshiEric GlasgowAlexander LekanSeema AgarwalGary D LukerHossein Tavana

Published in: BMC cancer (2020)

We established that fisetin and quercetin potently inhibit migration of metastatic TNBC cells by interfering with activities of oncogenic protein kinases in multiple pathways.

Keyphrases

induced apoptosis
cell cycle arrest
squamous cell carcinoma
small cell lung cancer
transcription factor
endoplasmic reticulum stress
protein protein
cell death
oxidative stress
signaling pathway
amino acid
protein kinase
small molecule
cell proliferation