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Reducing Neuron Apoptosis in the Pontine Micturition Center by Nerve Root Transfer for Restoration of Micturition Function after Spinal Cord Injury.

Ronghua YuGang YinJianguo ZhaoHuihao ChenDepeng MengJiaqiang ZhangYaofa LinZheng XieChunlin HouHaodong Lin
Published in: BioMed research international (2020)
These findings demonstrate that lumbosacral nerve transfer can reduce neuronal apoptosis in the pontine micturition center and enhance functional recovery of neurons. This result further suggests that lumbosacral nerve transfer can be used as a new approach for reconstructing bladder function after spinal cord injury.
Keyphrases
  • oxidative stress
  • endoplasmic reticulum stress
  • peripheral nerve
  • cell cycle arrest
  • cell death
  • spinal cord injury
  • spinal cord
  • cell proliferation
  • urinary tract