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Development of a chitosan-modified PLGA nanoparticle vaccine for protection against Escherichia coli K1 caused meningitis in mice.

Jin ZhangHongwu SunChen GaoYing WangXin ChengYun YangQiang GouLanghuang LeiYanping ChenXingyong WangQuanming ZouJiang Gu
Published in: Journal of nanobiotechnology (2021)
We identified an effective strategy to improve the stability of Vo to maintain its immunogenicity, which will contribute to the future development of vaccines against E. coli K1.
Keyphrases
  • escherichia coli
  • drug delivery
  • high fat diet induced
  • metabolic syndrome
  • insulin resistance
  • klebsiella pneumoniae
  • multidrug resistant
  • pseudomonas aeruginosa