Occult hepatitis B virus infection in patients with chronic liver disease of different etiology in a Brazilian referral center: comparison of two different hepatitis B virus deoxyribonucleic acid amplification protocols: a cross-sectional study.
Alessandra Coutinho de FariaBernardo Henrique Mendes CorreaLuciana Costa FariaPaula Vieira Teixeira VidigalMarcelo Antônio Pascoal XavierTeresa Cristina de Abreu FerrariPublished in: Sao Paulo medical journal = Revista paulista de medicina (2022)
In addition to the differences in the prevalence of HBV infection in different regions, variations in the polymerase chain reaction technique used for HBV DNA amplification may be responsible for the large variations in the prevalence of OBI identified in different studies. There is a need for better standardization of the diagnostic methods used to diagnose this entity.