The Basophil Activation Test reduces the need for a food challenge test in children suspected of IgE-mediated cow's milk allergy.
Janneke Ruinemans-KoertsYvonne Schmidt-HieltjesAd JansenHuub F J SavelkoulAnnejet PlaisierPetra van SettenPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2018)
The BAT seems reliable and cost-effective to diagnose patients with an IgE-mediated cow's milk allergy. In IgE-sensitized patients, a BAT might replace a DBPCFC. For non-IgE-sensitized patients presenting with mild symptoms, we propose to consider a (double-blind) extended (time) challenge test at home.