Alteration of the mare's immune system by the synthetic progestin, altrenogest.
Carleigh Elizabeth FedorkaBarry A BallOlivia F WalkerAlan J ConleyCynthia J CorbinKristina G LuJessica M HannemanMats H T TroedssonAmanda A AdamsPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2019)
P4 and ALT appear to alter the immune system of the non-pregnant mare both systemically in addition to locally within the endometrium. Further research is necessary to determine the pathways through which this synthetic progestin functions on the immune system of the horse, and the consequences it may have.
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