Patients with PWS and related syndromes display differentially methylated regions involved in neurodevelopmental and nutritional trajectory.

Juliette SallesSanaa EddiryEmmanuelle LacassagneVirginie LaurierCatherine MolinasÉric BiethNicolas FranchittoJean-Pierre SallesMaithé Tauber

Published in: Clinical epigenetics (2021)

The PWS is associated with epigenetic modifications with differences in SNORD116 and MAGEL2 mutations, which seem to be relevant to the different associated phenotypes.

Keyphrases

dna methylation
gene expression
congenital heart disease
drug induced