Inhibiting interferon-γ induced cancer intrinsic TNFRSF14 elevation restrains the malignant progression of glioblastoma.

Yunhe HanCunyi ZouTianqi LiuWen ChengPeng ChengAn-Hua Wu

Published in: Journal of experimental & clinical cancer research : CR (2024)

Our findings highlight a malignant TNFRSF14/FAK axis as a potential target to blunt cancer-intrinsic resistance to ICB treatment, which may help improve the therapeutic efficiency of immunotherapy in malignancies.

Keyphrases

papillary thyroid
squamous cell
high glucose
squamous cell carcinoma
childhood cancer
young adults
diabetic rats
immune response
risk assessment
climate change
human health
endothelial cells