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Empowering the detection of ChIP-seq "basic peaks" (bPeaks) in small eukaryotic genomes with a web user-interactive interface.

Thomas DeneckerGaëlle Lelandais
Published in: BMC research notes (2018)
We developed a new bPeaks application (bPeaks App). The application allows the user to perform all the peak-calling analysis steps with bPeaks in a few mouse clicks via a web browser. We added new features relative to the original R package, particularly the possibility to import personal annotation files to compare the location of the detected peaks with specific genomic elements of interest of the user, in any organism, and a new organization of the result files which are directly manageable via a user-interactive genome browser. This significantly improves the ability of the user to explore all detected basic peaks in detail.
Keyphrases
  • genome wide
  • rna seq
  • high throughput
  • single cell
  • circulating tumor cells
  • label free
  • loop mediated isothermal amplification
  • sensitive detection