Reduced fibre size, capillary supply and mitochondrial activity in constitutional thinness' skeletal muscle.
Bogdan GaluscaJ VerneyE MeugnierY LingP EdouardL FeassonM RavelojaonaH VidalB EstourN GermainPublished in: Acta physiologica (Oxford, England) (2018)
Diminished type I fibres, decreased mitochondrial and metabolic activity suggested by these results are discordant with normal resting metabolic rate of CT subjects. Downregulated genes related to cytoskeletal proteins and myocyte differentiation could account for CT's resistance to weight gain.
Keyphrases
- weight gain
- skeletal muscle
- oxidative stress
- body mass index
- image quality
- computed tomography
- dual energy
- birth weight
- contrast enhanced
- genome wide
- heart rate
- positron emission tomography
- insulin resistance
- heart rate variability
- type diabetes
- magnetic resonance imaging
- physical activity
- adipose tissue
- genome wide identification