No polymorphisms in K13-propeller gene associated with artemisinin resistance in Plasmodium falciparum isolated from Brazzaville, Republic of Congo.
Pembe Issamou MayengueRoch Fabien NiamaDezi Kouhounina BatsimbaAlida Malonga-MassangaIgor LouzoloNadia Claricelle Loukabou BongoloLucette MacossoReyna Ibara OttiaGhyslain Kimbassa NgomaLouis Régis Dossou-YovoBrice Pembet SinganaGabriel AhomboGéril Sekangue ObiliSimon Charles KobawilaHenri Joseph ParraPublished in: BMC infectious diseases (2018)
The current study shows a very limited polymorphism in the K13-propeller gene in isolates from the Republic of Congo and K13 polymorphisms associate with ACT resistance are not present in this country. However, permanent and large surveillance of resistant parasite population using K13-propeller gene is recommended.