Temporal Changes of Clomiphene on Testosterone Levels and Semen Parameters in Subfertile Men.
Sriram V EleswarapuJohn T SigalosVadim OsadchiyAlvaro SantamariaMichael H ZhengNeilufar ModiriKeith V RegetsJesse Nelson MillsSriram Venkata EleswarapuPublished in: The world journal of men's health (2022)
Duration of treatment with clomiphene may impact testosterone and sperm concentration, and the historical 3 month milestone may be insufficient for clinical and research evaluation. Men taking CC may experience plateau in TT at 6 months and first benefit in sperm concentration at 9 months.