The Effect of Continuous Positive Airway Pressure (CPAP) Therapy on Serum Caspase-3 Level in Patients with Obstructive Sleep Apnea (OSA).

Mustafa Kemal Kaypak Ali Nihat Annakkaya Fatih Davran Pinar Yıldız Gülhan Uğur Yüregir

Published in: Sleep & breathing = Schlaf & Atmung (2024)

The results of this study did not reveal a relationship between the severity of OSA and caspase-3 levels. However, blood caspase-3 levels decreased as treatment compliance increased, suggesting that CPAP treatment may correct increased apoptosis in OSA. There is a need for more comprehensive studies on this issue.

Keyphrases

obstructive sleep apnea
positive airway pressure
sleep apnea
cell death
induced apoptosis
oxidative stress
endoplasmic reticulum stress
mesenchymal stem cells
dna methylation
cell cycle arrest
gene expression
cell therapy
pi k akt