Novel genomic prognostic biomarkers for dogs with cancer.

Esther ChonSharadha SakthikumarMin TangMatthew J HamiltonAndrew VaughanAshley SmithBreann SommerCecilia RobatChristina ManleyChristine MullinEmi OhashiEmily ManorJames CustisJoanne IntileKai Biu ShiuLisa ParshleyNoelle BergmanSabina Sheppard-OlivaresScott HafemanZachary WrightDavid HaworthWilliam HendricksGuannan Wang

Published in: Journal of veterinary internal medicine (2023)

We identified novel mutations with prognostic value and demonstrate the benefit of targeted treatment across multiple cancer types. These results provide clinical evidence of the potential for genomics and precision medicine in dogs with cancer.

Keyphrases

papillary thyroid
squamous cell
lymph node metastasis
squamous cell carcinoma
gene expression
single cell
cancer therapy
climate change
genome wide
combination therapy
human health