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Loss of OTUD6B Stimulates Angiogenesis and Promotes Diabetic Atherosclerosis.

Zhongqun WangLili ZhangLihua LiMengxue Zhou
Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2022)
OTUD6B can reduce angiogenesis in atherosclerotic plaques, enhance plaque stability and delay the progression of atherosclerosis by regulating the proliferation, migration, and lumen formation of endothelial cells.
Keyphrases
  • endothelial cells
  • vascular endothelial growth factor
  • wound healing
  • cardiovascular disease
  • high glucose
  • type diabetes
  • signaling pathway
  • coronary artery disease