Synthetic surfactant with a recombinant surfactant protein C analogue improves lung function and attenuates inflammation in a model of acute respiratory distress syndrome in adult rabbits.

J Zebialowicz AhlströmF MassaroP MikolkaR FeinsteinG PerchiazziO Basabe-BurgosT CurstedtA LarssonJ JohanssonAnna Rising

Published in: Respiratory research (2019)

This study indicates that treatment of experimental ARDS with synthetic lung surfactant based on rSP-C33Leu improves lung function and attenuates inflammation.

Keyphrases

lung function
acute respiratory distress syndrome
extracorporeal membrane oxygenation
cystic fibrosis
chronic obstructive pulmonary disease
mechanical ventilation
air pollution
oxidative stress
intensive care unit
young adults
protein protein
cell free
childhood cancer