Model Informed Precision Dosing Tool Forecasts Trough Infliximab and Associates with Disease Status and Tumor Necrosis Factor-Alpha Levels of Inflammatory Bowel Diseases.

Christian Primas Walter Reinisch John Carl PanettaAlexander EserDiane R MouldThierry Dervieux

Published in: Journal of clinical medicine (2022)

These data establish the value of our MIPD tool in forecasting trough IFX levels in patients with IBD. Serum TNF-α and CRP are reflective of inflammatory burden which impacts exposure.

Keyphrases

rheumatoid arthritis
ulcerative colitis
oxidative stress
electronic health record
machine learning
deep learning