Role of Porphyromonas gingivalis in oral squamous cell carcinoma development: A systematic review.

Irene Lafuente-Ibáñez de MendozaXabier Maritxalar MendiaAna María García de la FuenteGuillermo Quindós AndrésJosé Manuel Aguirre Urizar

Published in: Journal of periodontal research (2019)

Porphyromonas gingivalis could play an important role in OSCC development and could be involved in three different stages: epithelial-mesenchymal transition of malignant cells, neoplastic proliferation, and tumor invasion. Current findings emphasize the convenience of treatment and control approaches of PD as part of the primary prevention of OSCC.

Keyphrases

epithelial mesenchymal transition
induced apoptosis
signaling pathway
cell cycle arrest
cell migration
oxidative stress
cell death
combination therapy
pi k akt