Optimization of Lung Surfactant Coating of siRNA Polyplexes for Pulmonary Delivery.

Domizia BaldassiThi My Hanh NgoOlivia M Merkel

Published in: Pharmaceutical research (2022)

The addition of a coating with pulmonary surfactant to polymeric cationic polyplexes represents a valuable formulation strategy to improve local delivery of siRNA to the lungs.

Keyphrases

cancer therapy
drug delivery

pulmonary hypertension

hyaluronic acid

drug release