Optimization of Lung Surfactant Coating of siRNA Polyplexes for Pulmonary Delivery.
Domizia BaldassiThi My Hanh NgoOlivia M MerkelPublished in: Pharmaceutical research (2022)
The addition of a coating with pulmonary surfactant to polymeric cationic polyplexes represents a valuable formulation strategy to improve local delivery of siRNA to the lungs.