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An Epigenetic Signature is Associated with Serum 25-Hydroxyvitamin D in Colorectal Cancer Tumors.

Hatim BoughanemAndrea G IzquierdoPablo Hernandez-AlonsoIsabel Arranz-SalasFelipe F CasanuevaFrancisco J TinahonesAna B CrujeirasManuel Macias-González
Published in: Molecular nutrition & food research (2021)
This study identifies novel epigenetic loci associated with serum 25(OH)D status. Interestingly, also, a positive association between vitamin D and DNA methylation in the CRC context is found, suggesting a role in CRC. Further studies are warranted to clarify and replicate these results.
Keyphrases
  • dna methylation
  • genome wide
  • gene expression
  • copy number
  • genome wide association study
  • genome wide association