An Epigenetic Signature is Associated with Serum 25-Hydroxyvitamin D in Colorectal Cancer Tumors.

Hatim BoughanemAndrea G IzquierdoPablo Hernandez-AlonsoIsabel Arranz-SalasFelipe F CasanuevaFrancisco J TinahonesAna B CrujeirasManuel Macias-González

Published in: Molecular nutrition & food research (2021)

This study identifies novel epigenetic loci associated with serum 25(OH)D status. Interestingly, also, a positive association between vitamin D and DNA methylation in the CRC context is found, suggesting a role in CRC. Further studies are warranted to clarify and replicate these results.

Keyphrases

dna methylation
genome wide
gene expression
copy number
genome wide association study
genome wide association