XJ-8, a natural compound isolated from Sanguis draxonis, inhibits platelet function and thrombosis by targeting MAP3K3.

Zhixiang ZhuLili WangRan GuoDaoran PangWenxuan WangYan WuNing WeiJun LiPengfei Tu

Published in: Journal of thrombosis and haemostasis : JTH (2021)

XJ-8 can inhibit platelet function and thrombosis by targeting MAP3K3 and has potential to be developed into a novel therapeutic agent for the treatment of thrombotic diseases.

Keyphrases

pulmonary embolism
high density
combination therapy