Nicotinamide N-methyltransferase in nonmelanoma skin cancers.
Veronica PompeiEleonora SalvoliniCorrado RubiniGuendalina LucariniElisa MolinelliValerio BrisigottiValentina PozziDavide SartiniAnna CampanatiAnnamaria OffidaniMonica EmanuelliPublished in: European journal of clinical investigation (2019)
These evidences seem to demonstrate that the different NNMT dysregulation detected in BCC and SCC may be the result of important biological traits distinctively characterizing these two forms within NMSCs. In addition, enzyme levels seem to be inversely correlated with tumour aggressiveness, thus suggesting the potential suitability of the enzyme as a prognostic biomarker for both neoplasms.