Reply.
Dana E OrangeNathalie E BlachereMayu O FrankSalina ParveenEdward F DiCarloSerene MirzaTania PannelliniMark P FiggieVivian P BykerkCaroline S JiangEllen M GravalleseAna Maria OrbaiSarah L MackieSusan M GoodmanPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2020)
We are very grateful for the interest in our manuscript describing synovial histology features that associate with patient reports of morning stiffness in rheumatoid arthritis(RA)1 . Pamuk et al. note that neutrophil gene and protein expression, as well as cell counts, fluctuate in the blood in a 24-hour circadian cycle and the circadian variation in neutrophil function may contribute to morning stiffness.